The process of aging involves multiple biologic pathways, acting simultaneously. Current interventions, tend to be ineffective, because they are unable to address a single root cause. However, recently, scientists recently. discovered, that circadian rhythms , present in most cells, orchestrate most functions essential to life and play an important role in the aging process, itself.
Circadian rhythms could play a critical role.
Almost all aspects of cellular physiological functions are controlled by the biological clock including; bioenergetic, neurologic & metabolic health. Clock disruptions lead to oxidative stress, inflammation, and even microbiome alterations, that are linked to a myriad of health problems, including; Alzheimer’s Disease, metabolic syndrome, obesity, depression & more.
Restoring circadian function is a promising, and completely new approach to addressing a multitude of chronic conditions that ultimately promote healthy aging.
Science Combined with Nature Offers a New Approach to Aging
Circadian Rhythms Change with Age, Causing Many Health Problems
Researchers, have shown that daily rhythm tends to change with age and environmental factors.
The amplitude, that is highest point of the circadian oscillation, during a 24hr cycle, shortens, with age.
Disrupted rhythms are linked to inflammation, oxidation, and many age-related diseases such as depression, cognition disorders, physical decline, cancer, metabolic disorder, microbiome imbalances, and skin pathogenesis.
A Bioflavonoid that Restores
Circadian Rhythms to Enhance Health & Longevity
Scientists screened a quarter million compounds, to discover a promising group of compounds bioflavonoids, called polymethoxylated flavones (PMFs) that bind &control clock genes to affect many biological pathways:
Anti-inflammatory, anticancer, antioxidant, neuroprotective, metabolic and cardio-protective
In studies, some bioflavonoids, (PMFs), restored circadian rhythms, resulting in health benefits (weight loss, energy, mood, cognitive).
Addressing Bioavailability
Most bioflavonoids have low stability, permeability and solubility, in addition to poor bioavailability, and therefore, the benefits of bioflavonoids observed in animals are difficult to achieve in humans.
Select bioflavonoids are transformed, and purified into derivatives called VITAMIN P ™ .
Further enhancements improve the pharmaco-kinetics of VITAMIN P ™ resulting in new proprietary derivatives of Vitamin P ™.
Technology enables bioflavonoid delivery to target tissues at therapeutic doses, in humans for the first time.Both the carrier technology as well as the bioactives are completely naturally-derived and safe for topical and/or systemic applications
The DeepSense prodrugs have been optimized to achieve optimum physical and chemical properties in terms of membrane permeation, bioavailbility, and stability.
Lipid Encapsulation Technology Transforms Citrus-Derived Flavonoids into Bioavailable Functional Substances
Unique Mechanism of Action; Binding & Controlling Clock Genes to Improve Health Markers
Aging, unhealthy. adults display dampened circadian amplitudes
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VITAMIN P™ easily absorbs into tissues , binding to Retinoic Orphan Receptor (ROR), which regulate clock genes
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Key longevity, bioenergy, immune, & metabolic targets, are subject to rhythmicity
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